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Experimentation & Causal Inference
A/B tests, randomized trials and the methods that separate cause from correlation.
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Latest in Experimentation & Causal Inference
The emerging AI decision in clinical trials: controlled vs. open framework
4+ day, 23+ hour ago (14+ words) Clinical Trials Arena...
Causal multi-modal AI predicts who benefits from chemotherapy — and who will not
5+ day, 21+ hour ago (510+ words) Authors: Dhruva Biswas and Krzysztof J. Geras AI-enabled perception of how treatment choice shapes patient trajectories. Causal multi-modal AI turns routine pathology and clinical data into personalized estimates of chemosensitivity, separating risk of recurrence from treatment benefit to help direct chemotherapy…...
AI innovation is reshaping healthcare from diagnosis to drug discovery
6+ day, 1+ hour ago (486+ words) In science fiction, futuristic medical technology often appears in a doctor’s hand. Think of Dr. McCoy scanning a patient using a tricorder wand in Star Trek. These innovations are making diagnosis faster. But can they make it better? Early evidence…...
AI Learns to Predict Patient Outcomes Even When Key Omics Data Are Missing
1+ week, 1+ day ago (754+ words) Precision medicine has long promised a future in which a patient’s treatment is tailored to the molecular signatures written into their genome, transcriptome, epigenome, proteome and metabolome....
From AI to the death of the default: what cancer science will look like in 2036 - Cancer Research UK - Cancer News
1+ week, 4+ day ago (490+ words) From the increasing role of tech to better representing the population, what will research look like in 2036? We asked two researchers to do a spot of future gazing and give us their predictions for the next decade… Ed Roberts runs…...
Insilico’s AI-designed drug shows an early aging signal in lung disease patients
1+ week, 4+ day ago (574+ words) Insilico’s rentosertib shifted aging clock estimates in a small study, offering an early glimpse of AI’s medical promise while leaving major questions. Insilico Medicine has published an exploratory analysis showing that rentosertib, a drug candidate designed with AI, shifted blood…...
An AI-developed drug appeared to make patients biologically younger in a clinical trial
1+ week, 5+ day ago (44+ words) The experimental drug, rentosertib, comes from Insilico Medicine and was developed to treat idiopathic pulmonary fibrosis, a disease that progressively scars the lungs....
AI in clinical trials: Building better trials before they start
1+ week, 5+ day ago (809+ words) Drug development is an inherently risky endeavour, with the average probability of approval for a drug entering Phase I studies now sitting at just 6.7%. While much of this can be attributed to lack of efficacy, factors such as poor clinical…...
AI-Designed Drug Cuts Biological Age in a 42-Patient Trial
1+ week, 5+ day ago (797+ words) Insilico Medicine published a study in Nature Biotechnology on Monday reporting that rentosertib, a drug designed by generative AI, reduced predicted biological age in patients who took it. Six independently built aging clocks all pointed the same way. The company’s…...
Illustrated, chemical structure of LSD
1+ week, 5+ day ago (75+ words) (IMAGE) EurekAlert! In this illustration, the chemical structure of LSD — represented by a rainbow — is being deconstructed into simplified analogues, which are portrayed as individual colors. Illustrated by Andras Domokos and Andrian G. Basargin/UC Davis Credit must be given…...